WebNov 1, 2006 · We previously reported that cholesteryl pullulan (CHP) deriva-tives were effective carriers drug delivery systems in targeting cancer cells. We have now synthesized folic acid-conjugated CHP... WebMar 22, 2024 · We have been developing the cholesteryl pullulan (CHP)-antigen protein nanoparticle as a cancer vaccine for esophageal cancer [ 13, 14 ]. A CHP nanoparticle that contains a tumor antigen is a new type of cancer vaccine with a novel antigen delivery system for both the MHC class I and class II pathways.
Cholesteryl Pullulan Encapsulated TNF-α Nanoparticles Are an Eff…
WebPullulan is mainly used by the cell to resist desiccation and predation. The presence of this polysaccharide also facilitates diffusion of molecules both into and out of the cell. The … WebNov 19, 2015 · A self-assembled nanogel is constructed from light-sensitive cholesteryl pullulan (Ls-CHP) by using photo-labile ortho-nitrobenzyl (o-NB) units. The nanogel-based film is obtained by evaporation of an Ls-CHP nanogel solution. Exposure of the resulting nanogel-based film to light with a mask resulted in a pat nourish good food belfast
First-in-human phase I clinical trial of the NY-ESO-1 protein cancer ...
WebJan 2, 2014 · The cholesteryl pullulan, with an average degree of substitution of 5.4 per 100 glucose units, was prepared by reacting pullulan with cholesterol succinate according to a procedure already reported (Yang et al., 2010), and the structure of CHSP is shown in Fig. 1. Download : Download full-size image; Fig. 1. The synthesis route of Bio-CHSP. WebThe CHP-HER2 vaccine, comprising truncated 146HER2 protein complexed with nanogels of cholesteryl pullulan (CHP), is a novel protein antigen vaccine that elicits 146HER2-specific CD8 (+) and CD4 (+) T-cell immune responses in … WebHere, we synthesized cholesteryl-modified aminated pullulan polymers (CHPNs) with different amounts of cholesterol succinate (CHS). We characterized the three hydrophobically modified polymers (CHPN 1, … nourish guide