WebFeb 22, 2024 · Stable over-overexpression of wild-type CTSB (CTSB wt/hi), but not of an CTSB active site mutant (CTSB N298A), rescued cell growth in CTSB knockdown cells and abolished the efficacy of VEGFR TKI ... WebOct 20, 2013 · Moreover, CTSB, Shh and Ptch were up-regulated in patients with metastatic lung SCC, suggesting that hedgehog signaling might be activated in metastatic lung SCC which could affect the expression of CTSB that influence the invasive activity of lung SCC. These data suggested that CTSB might serve as a prognostic and therapeutic marker for …
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WebOct 10, 2024 · How glucose metabolism remodels pro-tumor functions of tumor-associated macrophages (TAMs) needs further investigation. Here we show that M2-like TAMs bear … WebJun 21, 2005 · Tandem duplications in a non-coding genomic region containing an active enhancer element for CTSB result in CTSB abnormal expression with pathological consequences 1 publication. Description. An autosomal dominant genodermatosis characterized by recurrent episodes of palmoplantar erythema and epidermal peeling … irs e-file business returns
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