Dynein heavy chain 2
WebNov 2, 2010 · Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the head or motor domain. The … WebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm dyneins; (iii) non-axonemal (‘cytoplasmic’) dynein-1, also called MAP1C, Dhc1a and Dyh1; and (iv) cytoplasmic dynein-2, also called Dhc1b and Dyh2 ...
Dynein heavy chain 2
Did you know?
WebTo test if this is the case in C. elegans, we generated worm strains stably coexpressing mCherry:histone H2B and GFP:fusions of cytoplasmic dynein heavy chain DHC-1 or dynamitin DNC-2. Both fusion proteins localized diffusely to the spindle and the spindle poles in mitosis and significant enrichment at kinetochores over the spindle signal was ... WebDec 8, 2024 · XM_017018291.2 → XP_016873780.1 cytoplasmic dynein 2 heavy chain 1 isoform X2. XM_006718903.3 → XP_006718966.1 cytoplasmic dynein 2 heavy chain 1 isoform X1. Conserved Domains (7) summary pfam03028 Location: 3608 → 4289 Dynein_heavy; Dynein heavy chain and region D6 of dynein motor pfam07728 …
WebGene ID: 127280596, updated on 31-Oct-2024. Summary Other designations. cytoplasmic dynein 2 heavy chain 1 WebDYNC2H1 is the central ATPase subunit of the IFT dynein-2 complex, the principal minus-end directed microtubule motor that drives retrograde transport of the IFT-A protein …
WebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm …
WebA rapid procedure for fractionating salt-stable dynein subunits from high-salt extracts of Chlamydomonas axonemes has been developed using a high-pressure liquid chromatography system with an anion exchange column and gradient salt elution. Five distinct fractions are shown to be highly enriched for five distinct subunits or subunit …
WebOct 29, 2024 · The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH9 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996; Milisav et al., 1996). DNAH9 localizes to the distal axoneme portion of type 2 outer dynein arms (summary by Fassad … drinking air freshener side effectsWebNov 7, 2005 · Only a single heavy chain gene has been identified for the initially described form of cytoplasmic dynein, but two intermediate chain and two light intermediate chain genes have been found (Mikami et al., 1993; Zhang et al., 1993; Gill et al., 1994; Hughes et al., 1995; Vaughan and Vallee, 1995). epc free gamesWebAug 26, 2024 · The two identical copies of the dynein-2 heavy chain are contorted into different conformations by a WDR60−WDR34 heterodimer and a block of two RB and six … Metrics - Structure of the dynein-2 complex and its assembly with intraflagellar ... drinking alcohol after bypass heart surgeryWebMay 1, 2001 · The most highly divergent portion of the heavy chain sequence is the N-terminal ∼1300 residues. This portion of the protein forms the relatively short tail of dynein, and its sequence is best correlated with the functional class of the dynein isoform 6, 7, 8.Interactions within the N-terminal domain are important for heavy chain dimerization 8, … drinking alcohol after a cleanseWebFeb 6, 2024 · In a recent study, Chaaban and Carter use cryo-electron microscopy (cryo-EM) and an innovative data-processing pipeline to determine the first high-resolution structure of the dynein–dynactin–BICDR1 complex assembled on microtubules. The structure of the complex reveals novel stoichiometry and provides new mechanistic … drinking alcohol after prp hair treatmentWebJun 26, 2011 · Dynein-2 is a putative retrograde IFT motor, which transports IFT particles from the ciliary tip toward the cell body . Recent studies have shown that deficits of dynein-2 heavy chain (HC) cause some human … drinking aids for the elderlyWebMay 1, 2001 · The most highly divergent portion of the heavy chain sequence is the N-terminal ∼1300 residues. This portion of the protein forms the relatively short tail of … epc free