Florence imrt trial

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August undefined, 2024

WebApr 7, 2014 · Lorenzo Livi, Full Professor; Chief Radiotherapy-Oncology Unit; Florence University, Azienda Ospedaliero-Universitaria Careggi: ClinicalTrials.gov Identifier: … WebOct 17, 2024 · To date, only the Florence IMRT-APBI phase 3 trial reported the outcomes of exclusive IMRT accelerated PBI compared to WBI, demonstrating no significant difference between the two groups in terms of ipsilateral breast tumor recurrences (IBTR). The PBI group presented significantly better results considering acute (p=0.0001), late (p=0.004), …

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WebFeb 15, 2024 · Abstract. Background. Partial breast irradiation (PBI) is a reasonable alternative for a whole breast irradiation (WBI) in selected early stage breast cancer patients. The 5-year analysis of the APBI IMRT Florence phase 3 trial showed no significant difference in terms of ipsilateral tumor recurrence (IBTR) and survival rates between the … WebJun 1, 2024 · The APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective partial breast irradiation schedule, with long-term … flow if else expression

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WebNational Center for Biotechnology Information WebAPBI-IMRT-Florence trial Delivery technique In the original protocol (NCT02104895), ﬁve 6-MV step-and-shoot IMRT coplanar ﬁelds were used.10 A dose of 30 Gy in 5 nonconsecutive, once-daily fractions was prescribed. At the time of the study design, the every-other-day approach was chosen to be cautious in regard to the toxicity proﬁle. WebSep 15, 2024 · In the Florence trial, 30 Gy in five daily fractions was used for PBI with intensity-modulated radiotherapy (IMRT), and treatment-related toxicity and cosmesis outcomes were found to be significantly in favor of … flowies corner

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Updates on the APBI-IMRT-Florence Trial (NCT02104895 …

WebJan 28, 2024 · The Florence IMRT trial which delivered EB-APBI with 5 fractions of 6 Gy every other day showed similar results to conventionally fractionated whole-breast radiotherapy; however it was not powered to demonstrate non-inferiority [21, 22]. Webclinical trial between March 2005 and June 2013 at the Radiation Oncology Unit of the University of Florence (Florence, Italy). The study aimed to compare tangential ﬁelds … flowies corner githubWebJul 10, 2024 · From 2012 to 2015, 289 patients were enrolled, of whom 278 were eligible. Between baseline and end of RT, the mean EPIC bowel score declined 23.6 points in the standard RT group and 18.6 points in the … flow if expression

"WebAug 24, 2024 · PURPOSE To report the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) Florence … " - Florence imrt trial

Florence imrt trial

Intensity-modulated radiation therapy (IMRT) - Mayo Clinic

WebAug 30, 2024 · who randomized patients to intensity modulated radiation therapy (IMRT) APBI (30 Gy in 5 nonconsecutive daily fractions) versus conventionally fractionated WBI. … WebMar 28, 2024 · It is worth noting that ultra-fractionated EBRT options have also been increasingly adopted following the publication of the APBI-Florence-IMRT trial that demonstrated equivalent local control and survival of a 5-fraction partial-breast EBRT regimen compared to conventional whole-breast irradiation (21). In this trial, the five …

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WebDec 11, 2024 · A fourth study, the Florence trial, 13 used the QLQ-BR23 subscale, but only at baseline and 2 years after completion of treatment. Patients were randomly assigned to partial-breast IMRT using 30 Gy in … WebMar 9, 2024 · Mayo Clinic doctors use the latest imaging techniques to carefully plan radiation treatments. Doctors use CT scans, MRI scans and positron emission …

WebThe APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective partial breast … WebAug 24, 2024 · The Florence trial showed equivalent outcomes for WBI (50 Gy in 25 fractions with tumor bed boost) vs. APBI (30 Gy in five every-other-day fractions) using IMRT.

WebDec 15, 2024 · APBI-IMRT Florence Trial Primary endpoint: Ipsilateral breast tumor recurrence Median follow up: 10.7 years Meattiniet al., JCO 2024 520 patients enrolled 30 Gy in 5 fxQOD PBI, 1.5 weeks (n=260) 50Gy in 25 fx WBI, 5 weeks (n=260) 47 Toxicity Reduction in Breast Cancer APBI-IMRT Florence Trial Efficacy Meattiniet al., JCO 2024 48 WebJun 1, 2010 · Purpose: To evaluate with a randomized clinical trial the possibility of treating the index quadrant with external intensity-modulated radiotherapy (IMRT) in a selected group of patients with early-stage breast cancer and to analyze the acute toxicity. Methods and materials: From September 2005, a randomized Phase III clinical trial has been …

WebJan 1, 2024 · The APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective …

WebDec 10, 2024 · Purpose: To report the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) Florence … green care hof mellinghausenWebMar 9, 2024 · Mayo Clinic doctors use the latest imaging techniques to carefully plan radiation treatments. Doctors use CT scans, MRI scans and positron emission tomography scans, also called PET scans, to create a treatment plan that targets just the cancer. Proton beam therapy facilities at Mayo Clinic use intensity-modulated pencil beam scanning. flow if nullWebMay 25, 2024 · 566 Background: The impact of age on local recurrence rate of patients affected by early breast cancer is still unclear. The standard of care for older adult largely varies depending on patient- and tumor-related features, but also on national guidelines. We recently presented the 10 years median follow update of the APBI-IMRT Florence phase … flow if field is blankWebDec 5, 2024 · A trial of interstitial brachytherapy and another of non-accelerated (over 3 weeks) external beam partial breast radiotherapy reported similar rates of local recurrence compared with whole breast irradiation, but median follow-up was 6–6·6 years and few events were observed. ... (IMRT). External beam radiotherapy is non-invasive and uses ... green care harlowWebOct 22, 2024 · Meattini I, Poortmans PMP, Marrazzo L, Desideri I, Brain E, Hamaker M, Lambertini M, Miccinesi G, Russell N, Saieva C, Strnad V, Visani L, Kaidar-Person O, … green care homes clarksville tnWebOct 1, 2024 · Ten years results of the Canadian breast intensity modulated radiation therapy (IMRT) randomized controlled trial. Radiother Oncol, 121 (2016), pp. 414-419. Article. ... Long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol, 38 (2024), pp. 4175-4183. flow ifoodWebFeb 11, 2024 · ORCID: 0000–0001-6019–7309. In the treatment of breast cancer, intensity-modulated radiation therapy (IMRT) reportedly reduces the high-dose irradiation of at-risk organs and decreases the ... greencare import export limited