Web13 sep. 2024 · Markush structures are representations of chemical structures with variable substituents that are used in patent documents to specify groups of related chemical … Web5 apr. 2024 · Markush structures represent four main types of structural variation: substituent, positional, frequency, and homology. Substituent The functional group or …
2117-Markush Claims - United States Patent and Trademark Office
WebFurther, in this case, all of the alternative chemical compounds share the component 2,4-D. According to the analysis, the members of the Markush grouping do not share a substantial structural feature because “the members of the Markush group defining component (b) represent a plurality of chemical classes with varying structures.” Web1 jun. 2024 · A simple example is presented in Fig. 1. Given a series of specific compounds, the algorithm generates a Markush structure that encompasses all compounds along with other similar ones due to additional combinations of the variable parts derived from the original compounds. As Fig. 1 demonstrates, substituent variation (R-groups), position ... mobile homes for sale miamisburg ohio
Intelligent pharmaceutical patent search on a near-term gate …
Weband Nelson, 1990). Finally, Markush structures facilitate constructing ‘patent fences’ around an original drug (Cohen et al., 2000; Sternitzke, 2013) to the extent that patentees are allowed to file subsequent patent applications on selected molecules contained in a Markush structure . WebCombining textual information extraction methods with chemoCR TM for the multimodal information extraction of Markush structures from patents and from QSAR tables has not been addressed yet. There is an example patent page showing a Markush structure to left. This functionality will be part of future work. Web15 jun. 2024 · Typically, the drug product will be defined by its structure. For example, a chemical compound may be defined by a Markush structure or a specific chemical formula, and an antibody may be defined by the six CDR sequences that are required for binding. At the EPO, there can be some flexibility as to what level of structural definition is required. mobile homes for sale marysville wa 55+